863908-18-3Relevant academic research and scientific papers
Asymmetric synthesis of 1-substituted tetrahydro-3-benzazepines as NMDA receptor antagonists
Wirt, Ursula,Schepmann, Dirk,Wuensch, Bernhard
, p. 462 - 475 (2008/02/04)
A novel asymmetric synthesis of 1-substituted tetrahydro-3-benzazepines (R)-15 and (S)-15 has been performed. Starting with o-phenylenediacetic acid (1) and (R)-phenylglycinol as chiral auxiliary the tricyclic oxazololactam (3R)-10 was synthesized as key
Asymmetric synthesis of 1-substituted tetrahydro-3-benzoazepines
Wirt, Ursula,Froehlich, Roland,Wuensch, Bernhard
, p. 2199 - 2202 (2007/10/03)
In order to develop a new asymmetric synthesis of enantiomerically pure 1-substituted tetrahydro-3-benzoazepines 3, the synthesis of diastereomerically pure oxazolo[3]benzoazepinone 4 has been performed. The stereochemical information of the key intermedi
