863971-72-6Relevant academic research and scientific papers
Organic solvent-free, enantio- and diastereoselective, direct Mannich reaction in the presence of water
Hayashi, Yujiro,Urushima, Tatsuya,Aratake, Seiji,Okano, Tsubasa,Obi, Kazuki
, p. 21 - 24 (2008/09/17)
An organocatalyst-mediated, asymmetric Mannich reaction in the presence of water without using organic solvents has been developed. A highly reactive siloxytetrazole hybrid catalyst has been developed for the reaction of dimethoxyacetaldehyde, while the s
Efficient entry to amino sugars and derivatives via asymmetric organocatalytic Mannich reactions
Enders, Dieter,Grondal, Christoph,Vrettou, Marianna
, p. 3597 - 3604 (2008/03/14)
An efficient biomimetic C3+Cn entry to amino sugars and derivatives via a direct asymmetric organocatalytic Mannich methodology employing 2,2-dimethyl-1,3-dioxan-5-one as a dihydroxyacetone phosphate equivalent and N-PMP or N-Boc pro
Asymmetric synthesis of selectively protected amino sugars and derivatives by a direct organocatalytic mannich reaction
Enders, Dieter,Grondal, Christoph,Vrettou, Marianna,Raabe, Gerhard
, p. 4079 - 4083 (2007/10/03)
(Chemical Equation Presented) Short and sweet: Starting from the commercially available precursors 1-3, selectively protected amino sugars and derivatives are obtained in one step and with high diastereo- and enantiomeric purity by means of a proline-cata
