86400-14-8

Basic information

• Product Name: (R)-4-{(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-pentanoic acid 4-nitro-benzyl ester
• CAS NO: 86400-14-8
• Molecular Weight: 478.618
• Mol File: 86400-14-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-{(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-pentanoic acid 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-{(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-pentanoic acid 4-nitro-benzyl ester(86400-14-8)
• EPA Substance Registry System: (R)-4-{(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-pentanoic acid 4-nitro-benzyl ester(86400-14-8)

Safety Data

• Hazardous Substances Data: 86400-14-8(Hazardous Substances Data)

Upstream product

• 115026-51-2 (S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-azetidin-2-one 
• 105995-50-4 magnesium 4-nitrobenzyl malonate 
• 124667-64-7 (S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-((R)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl)-azetidin-2-one 

Relevant articles and documents

SYNTHESIS OF 1-β-METHYLCARBAPENEM KEY INTERMEDIATES INVOLVING THE LABILE ACYL AUXILIARY 4,4-DIMETHYL-1,3-OXAZOLIDINE-2-THIONE

A convenient synthesis of 1-β-methylcarbapenem key intermediates based on the facile displacement of the 4,4-dimethyl-1,3-oxazolidine-2-thione auxiliary of 5 is described.