864181-29-3

Upstream product

• 4526-56-1 2,4-dibromo-6-chlorophenol 
• 95-57-8 2-monochlorophenol 
• 864181-27-1 ethyl (2R,3S)-3-[4-(benzyloxy)-3-bromo-5-chlorophenyl]-2,3-dihydroxypropanoate 
• 864181-26-0 ethyl (2E)-3-[4-(benzyloxy)-3-bromo-5-chlorophenyl]acrylate 
• 864181-25-9 2-(benzyloxy)-1,5-dibromo-3-chlorobenzene 
• 864181-28-2 ethyl (2R,3S)-3-[4-(benzyloxy)-3-bromo-5-chlorophenyl]-3-hydroxy-2-{[(4-methylphenyl)sulfonyl]oxy}propanoate 

Downstream Products

• 864181-32-8 (2S,3S)-3-(4-Benzyloxy-3-bromo-5-chloro-phenyl)-2-tert-butoxycarbonylamino-3-hydroxy-propionic acid 
• 864181-30-6 ethyl (2S,3S)-3-[4-(benzyloxy)-3-bromo-5-chlorophenyl]-2-[(tert-butoxycarbonyl)amino]-3-hydroxypropanoate 

Relevant academic research and scientific papers

The first simple and efficient synthesis of the unusual dipeptide part of Phomopsin A

A practical high yielding synthesis of the key halogenated dipeptide part of Phomopsin A 2 is reported. The key steps are a selective Heck coupling, a Sharpless asymmetric dihydroxylation in PEG and a benzoyl isocyanate mediated synthesis of dehydrovaline