864381-91-9

Upstream product

• 166765-36-2 (2R,5S)-7-ethoxycarbonyl-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]oct-6-ene 
• 590-17-0 cyanomethyl bromide 

Downstream Products

• 864381-59-9 (2R,5S,6S)-6-(N-benzyloxycarbonyl-2-aminoethyl)-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]octane 
• 864381-75-9 [2-((2S,3S)-2-Hydroxymethyl-5-oxo-pyrrolidin-3-yl)-ethyl]-carbamic acid benzyl ester 
• 864381-62-4 (2R,5S,6S)-6-(carbamoylmethyl)-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]octane 
• 254909-28-9 (1S,2S,6R)-2-(5-aza-7-oxa-4-oxo-6-phenylbicyclo[3.3.0]oct-2-yl)ethanenitrile 

Relevant academic research and scientific papers

Stereoselective synthesis of conformationally constrained ω -amino acid analogues from pyroglutamic acid

Bicyclic lactams derived from pyroglutamic acid provide a useful scaffold for synthesis of conformationally restricted analogues of lysine, ornithine and glutamine, as well as an Ala-Ala dipeptide analogue. Amino alcohol and carboxylic acid derivatives ar