166765-36-2

Downstream Products

• 166765-37-3 (2R,5S,6S,11S)-11-ethoxycarbonyl-8,9-dimethyl-12-oxo-2-phenyl-1-aza-3-oxa-tricyclo[7.3.0^1,5.0^6,11]dodec-8-ene 
• 180334-91-2 (+)-(2R,5S,6R,7S)-7-Ethoxycarbonyl-6-[tris(ethoxycarbonyl)methyl]-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane 
• 204929-66-8 (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane 
• 195874-16-9 (2R,5S)-10-ethoxycarbonyl-11-oxo-2,8,9-triphenyl-1,8-diaza-3,7-dioxa-tricyclo[6.3.0^1,5.0^6,10]undecane 
• 254909-21-2 (3R,7S,7aS)-7-Cyanomethyl-5-oxo-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazole-6-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Functionalised pyrrolidinones derived from (S)-pyroglutamic acid by cycloaddition reactions

The α,β-unsaturatcd bicyclic lactams 3a,c, prepared from (S)-pyroglutamic acid, are useful substrates for cycloaddition reactions, giving excellent regio- and diastereocontrol; however, lactam 3c has very superior reactivity with several dienes and dipoles under mild reaction conditions.

A CONSISE APPROACH TO FUNCTIONALISED, HOMOCHIRAL PYRROLIDINONES

Acylation of O,N-acetal 1 gives excellent yields of the C-7 substituted products 2a,b.Alkylation of 2a under mild conditions gives high yields of the exo- 3 and endo- 4 substituted products in varying ratios, depending on the alkylating agent.The unsatura