86440-85-9Relevant academic research and scientific papers
Friedel-Crafts Aroylation of Benzene and Biphenyl in Methylene Chloride
Kumar, Shiv,Bhaduri, A. P.
, p. 17 - 22 (2007/10/02)
Reactions of acid chlorides of o-, m- and p-toluic acids, p-methoxy- and 3,4-methylenedioxybenzoic acids with biphenyl in the presence of anhydrous AlCl3 in methylene chloride have been studied.Of these, only the reactions of o-, m- and p-toluoly chlorides with biphenyl indicates inter- and intramolecular methylene insertions in the reaction products.It is observed that the 2-, 3- and 4-methylbenzophenones, formed as intermediates, participate in the methylene insertion reactions.In a few cases, besides methylene insertion, methyl insertion has also occurred.Unlike these reactions, the reaction of o-toluoyl chloride with benzene in presence of anhydrous AlCl3 in methylene chloride gives 2-methyl-3-(p-benzylphenyl)benzophenone.The structural assignment of these products are made on the basis of their PMR and mass spectra.
