864426-88-0Relevant articles and documents
Structure–activity relationship studies of 3-substituted pyrazoles as novel allosteric inhibitors of MALT1 protease
Asaba, Ken Nunettsu,Adachi, Yohei,Tokumaru, Kazuyuki,Watanabe, Akira,Goto, Yasufumi,Aoki, Takumi
, (2021/04/27)
We report the discovery of a novel series of 1,5-bisphenylpyrazoles as potent MALT1 inhibitors. Structure–activity relationship exploration of a hit compound led to a potent MALT1 inhibitor. Compound 33 showed strong activity against MALT1 (IC50/sub
Indolyl derivatives
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Page/Page column 19, (2010/02/14)
This invention relates to compounds of the formula I: wherein one of R6, R7 and R8 is and R1 to R15 and n are as defined in the description, and all enantiomers and pharmaceutically acceptable salts a