864437-38-7

Basic information

• Product Name: methyl 5-benzylthiazole-4-carboxylate
• Synonyms: methyl 5-benzylthiazole-4-carboxylate
• CAS NO: 864437-38-7
• Molecular Weight: 233.291
• Mol File: 864437-38-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 5-benzylthiazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-benzylthiazole-4-carboxylate(864437-38-7)
• EPA Substance Registry System: methyl 5-benzylthiazole-4-carboxylate(864437-38-7)

Safety Data

• Hazardous Substances Data: 864437-38-7(Hazardous Substances Data)

Upstream product

• 62167-00-4 DL-2-phenylthioacetic acid 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 864437-46-7 5-benzyl-thiazole-4-carboxylic acid 

Relevant articles and documents

One-pot four-component synthesis of polysubstituted thiazoles via cascade Ugi/Wittig cyclization starting from odorless Isocyano(triphenylphosphoranylidene)-acetates

A new one-pot four-component preparation of polysubstituted thiazoles by a cascade Ugi/Wittig cyclization has been developed. The four-component reactions of the odorless isocyano(triphenylphosphoranylidene)acetates 1, aldehydes 2, amines 3 and thiocarboxylic acids 4 produced 2,4,5-trisubstituted thiazoles 5 in moderate to good yields in the presence of triethylamine. The two-component reactions between isocyano(triphenylphosphoranylidene)acetates 1 and thiocarboxylic acids 4 in the presence of triethylamine provided the corresponding 4,5-disubstituted thiazoles 6 in good yields as well.