86452-60-0

Upstream product

• 110-89-4 piperidine 
• 96-48-0 4-butanolide 
• 4672-17-7 butane-4'-carboxy-(1'-piperidinyl)-carboxamide 
• 86452-70-2 C₁₂H₂₅NO₂Sn 

Downstream Products

• 94-62-2 Piperine 
• 94-62-2 piperine 
• 104683-09-2 Acetic acid 1-(benzenesulfonyl-benzo[1,3]dioxol-5-yl-methyl)-4-oxo-4-piperidin-1-yl-butyl ester 
• 104711-35-5 Acetic acid 1-(1-benzenesulfonyl-2-[1,3]dioxolan-2-yl-ethyl)-4-oxo-4-piperidin-1-yl-butyl ester 
• 104683-07-0 Acetic acid 2-benzenesulfonyl-1-(3-oxo-3-piperidin-1-yl-propyl)-heptyl ester 
• 104683-08-1 Acetic acid 2-benzenesulfonyl-4-methyl-1-(3-oxo-3-piperidin-1-yl-propyl)-pent-3-enyl ester 
• 111872-69-6 5-Benzenesulfonyl-4-hydroxy-1-piperidin-1-yl-decan-1-one 

Relevant academic research and scientific papers

A novel thermally latent anionic initiator. Polymerization of epoxide with hydroxylamide based on thermal dissociation

A novel thermally latent initiator system based on the thermal dissociation accompanying amide-ester exchange reaction is discussed. The key point of this initiator system is amide-ester exchange reaction releasing the amine by formation of a stable cyclic compound, although the nucleophilicity of the hydroxyl group is smaller than that of the amine. It is demonstrated that the hydroxylamides serve as excellent thermally latent non-salt-type initiators for polymerization of epoxide.

Chemoselective ruthenium-catalysed reduction of carboxylic acids

A very general and efficient catalytic protocol for the selective reduction of carboxylic acids to their corresponding alcohols under mild conditions is described. Various carboxylic acids, including benzoic acids, were reduced in good yields using the presented methodology. The ruthenium-catalysed method yields a highly chemoselective reduction permitting the reduction of a carboxylic acid functionality in the presence of numerous other potentially reducible moieties.

LiNTf2-catalyzed aminolysis of lactones with stoichiometric quantities of amines

LiNTf2 in the reaction of lactones with amines is able to activate cyclic esters towards ring opening, thus leading to clean open-chain amides under mild conditions and using a stoichiometric amount of amine. The generality of the method was demonstrated by a range of selected lactones and amines. Georg Thieme Verlag Stuttgart.

Tin(II) Amides: New Reagents for the Conversion of Esters to Amides

Mixed tin(II) amides are generated, in situ, via addition of aliphatic amines to Sn2.Condensation of these reagents with esters yields amides.

High-pressure Ammonolysis of Lactones to Hydroxyamides

The preparation of hydroxyamides from a variety of lactones and amines has been achieved at 9 kbar and 30 deg C or 65 deg C.The yields of hydroxyamides were excellent to moderate.

HIGHLY STEREOSELECTIVE SYNTHESIS OF (2E,4E)-DIENAMIDES AND (2E,4E)-DIENOATES VIA A DOUBLE ELIMINATION REACTION

Highly stereoselective synthesis of (2E,4E)-dienamides and (2E,4E)-dienoates was achieved through a double elimination reaction of β-acetoxy sulfones.