86452-60-0

Basic information

• Product Name: Piperidine, 1-(4-hydroxy-1-oxobutyl)-
• Synonyms: HO(CH2)3CON(CH2)5;4-hydroxy-1-(piperidin-1-yl)butan-1-one;4-oxo-4-(1-piperidinyl)-1-butanol;Piperidine,1-(4-hydroxy-1-oxobutyl)
• CAS NO: 86452-60-0
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.239
• Mol File: 86452-60-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-(4-hydroxy-1-oxobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-(4-hydroxy-1-oxobutyl)-(86452-60-0)
• EPA Substance Registry System: Piperidine, 1-(4-hydroxy-1-oxobutyl)-(86452-60-0)

Safety Data

• Hazardous Substances Data: 86452-60-0(Hazardous Substances Data)

Upstream product

• 4672-17-7 butane-4'-carboxy-(1'-piperidinyl)-carboxamide 
• 86452-70-2 C₁₂H₂₅NO₂Sn 
• 110-89-4 piperidine 
• 96-48-0 4-butanolide 

Downstream Products

• 94-62-2 Piperine 
• 94-62-2 piperine 
• 104683-09-2 Acetic acid 1-(benzenesulfonyl-benzo[1,3]dioxol-5-yl-methyl)-4-oxo-4-piperidin-1-yl-butyl ester 
• 104711-35-5 Acetic acid 1-(1-benzenesulfonyl-2-[1,3]dioxolan-2-yl-ethyl)-4-oxo-4-piperidin-1-yl-butyl ester 
• 104683-07-0 Acetic acid 2-benzenesulfonyl-1-(3-oxo-3-piperidin-1-yl-propyl)-heptyl ester 
• 104683-08-1 Acetic acid 2-benzenesulfonyl-4-methyl-1-(3-oxo-3-piperidin-1-yl-propyl)-pent-3-enyl ester 
• 111872-69-6 5-Benzenesulfonyl-4-hydroxy-1-piperidin-1-yl-decan-1-one 

Relevant articles and documents

A novel thermally latent anionic initiator. Polymerization of epoxide with hydroxylamide based on thermal dissociation

A novel thermally latent initiator system based on the thermal dissociation accompanying amide-ester exchange reaction is discussed. The key point of this initiator system is amide-ester exchange reaction releasing the amine by formation of a stable cyclic compound, although the nucleophilicity of the hydroxyl group is smaller than that of the amine. It is demonstrated that the hydroxylamides serve as excellent thermally latent non-salt-type initiators for polymerization of epoxide.

LiNTf2-catalyzed aminolysis of lactones with stoichiometric quantities of amines

LiNTf2 in the reaction of lactones with amines is able to activate cyclic esters towards ring opening, thus leading to clean open-chain amides under mild conditions and using a stoichiometric amount of amine. The generality of the method was demonstrated by a range of selected lactones and amines. Georg Thieme Verlag Stuttgart.

High-pressure aminolysis of lactones to hydroxy amides

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