864642-82-0

Basic information

• Product Name: 1-Bromo-3,5-dichloro-2-(2,2-difluoroethoxy)benzene
• Synonyms: Benzene, 1-bromo-3,5-dichloro-2-(2,2-difluoroethoxy)-
• CAS NO: 864642-82-0
• Molecular Formula: C₈H₅BrCl₂F₂O
• Molecular Weight: 305.9315
• Mol File: 864642-82-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 296.41°C at 760 mmHg
• Flash Point: 133.065°C
• Density: 1.687g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 1-Bromo-3,5-dichloro-2-(2,2-difluoroethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-3,5-dichloro-2-(2,2-difluoroethoxy)benzene(864642-82-0)
• EPA Substance Registry System: 1-Bromo-3,5-dichloro-2-(2,2-difluoroethoxy)benzene(864642-82-0)

Safety Data

• Hazardous Substances Data: 864642-82-0(Hazardous Substances Data)

Upstream product

• 120-83-2 2,4-dichlorophenol 
• 4524-77-0 2-bromo-4,6-dichlorophenol 
• 163035-65-2 methanesulfonic acid 2,2-difluoroethyl ester 
• 598-39-0 1,1-difluoro-2-iodoethane 
• 1095274-84-2 ethyl 3-chloro-5-(3-pyrrolidinyl)benzoate 
• 1168106-86-2 ethyl [4-[3-amino-1-azetidinyl]-5-(2-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetate 

Downstream Products

• 1160936-50-4 [3,5-dichloro-2-(2,2-difluoroethoxy)phenyl]boronic acid 
• 1392073-00-5 1-(2,2,2-trifluoroacetylamino)cyclopropanecarboxylic acid (rac)-{5-[3,5-dichloro-2-(2,2-difluoroethoxy)phenyl]indan-1-yl}amide 
• 1048975-77-4 C₂₀H₂₁Cl₂F₃N₂O₃ 

Relevant articles and documents

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

NEW BIARYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.

3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS

Claimed are intermediates in the synthesis of N-Arylmethyl-3-Oxo-2,3-dihydro- [1,2,4]triazolo[4,3-a]pyridine-6-carboxamides as well as a process (A) to arrive at 3-Oxo-2, 3-dihydro-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid. The triazolo[4,3-a]pyridine-6-carboxamides of formula (I) are used as soluble epoxide hydrolase inhibitors (sEH) having therapeutic effect in pathologic conditions such as hypertension, stroke, inflammatory processes, diabetes and a variety of cardiovascular diseases.