864722-48-5

Upstream product

• 1033823-80-1 C₁₈H₁₅NO₃ 
• 96-09-3 styrene oxide 
• 6052-63-7 2-phenylbut-3-en-1-ol 

Downstream Products

• 1132792-74-5 (+/-)-tert-butyl 2-phenylbut-3-enyloxycarbamate 
• 1393744-96-1 (±)-4-methyl-N-(2-phenylbut-3-enyloxy)benzenesulfonamide 
• 864722-39-4 N-(2-phenylbut-3-enyloxy)acetamide 

Relevant academic research and scientific papers

Stereoselective isoxazolidine synthesis via copper-catalyzed alkene aminooxygenation

Isoxazolidines are useful in organic synthesis, drug discovery, and chemical biology endeavors. A new stereoselective synthesis of methyleneoxy-substituted isoxazolidines is disclosed. The method involves copper-catalyzed aminooxygenation/cyclization of N

Influence of hydroxylamine conformation on stereocontrol in Pd-catalyzed isoxazolidine-forming reactions

Palladium-catalyzed carboamination reactions between N-Boc-O-(but-3-enyl) hydroxylamine derivatives and aryl or alkenyl bromides afford cis-3,5- and trans-4,5-disubstituted isoxazolidines in good yield with up to >20:1 dr. The diastereoselectivity observe

Stereoselective cyclization reactions of IBX-generated alkoxyamidyl radicals

In this paper, a method for the generation of alkoxyamidyl radicals is presented. These N-centered radicals can efficiently be formed starting from the corresponding acylated alkoxyamines using IBX as an oxidant. Stereoselective 5-exo and 6-exo reactions with these N-heteroatom-centered radicals leading to isoxazolidines and [1,2]oxazinanes are discussed. The N-O bond in the heterocycles can readily be cleaved with SmI2 to provide N-acylated 1,3-amino alcohols.