86474-73-9Relevant academic research and scientific papers
Preparation method of para-substituted aryl compound
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Paragraph 0530-0533, (2020/06/09)
The invention discloses a preparation method of a para-substituted aryl compound shown as a formula (I) which is described in the specfication. The preparation method is characterized by comprising the following step of: subjecting an aryl sulfonium salt shown as a formula (II) which is described in the specfication and boride to a coupling reaction in a solvent in an inert atmosphere under the action of alkali and a palladium catalyst to obtain the para-substituted aryl compound. According to the method, mono-substituted aromatic hydrocarbon is taken as a substrate, the aryl sulfonium salt isconstructed in situ, and the palladium catalyst catalyzes the aryl sulfonium salt constructed in situ to undergo the Suzuki-Miyaura coupling reaction, so a mono-substituted aromatic hydrocarbon para-arylation or alkenylation product is constructed quickly and efficiently. The method is mild in conditions, high in substrate universality and wide in tolerance of a heterocyclic coupling substrate.
N-heterocyclic carbene-palladium(II)-1-methylimidazole complex catalyzed Mizoroki-Heck reaction of aryl chlorides with styrenes
Gao, Ting-Ting,Jin, Ai-Ping,Shao, Li-Xiong
supporting information, p. 1916 - 1919 (2013/01/16)
A well-defined N-heterocyclic carbene-palladium(II)-1-methylimidazole [NHC-Pd(II)-Im] complex 1 was found to be an effective catalyst for the Mizoroki-Heck reaction of a variety of aryl chlorides with styrenes. Both activated and deactivated aryl chlorides work well to give the corresponding coupling products in good to excellent yields by using tetrabutylammonium bromide (TBAB) as the ionic liquid.
Synthesis of All of the Monomethyl Isomers of Naphthothiophene
Tominaga, Yoshinori,Tedjamulia, Marvin L.,Castle, Raymond N.,Lee, Milton L.
, p. 487 - 490 (2007/10/02)
All isomers of the monomethylnaphthothiophenes were synthesized by photocyclization of 2-styrylthiophenes which were either prepared by the Wadsworth-Emmons reaction or by the condensation of 2-lithiothiophene with the corresponding carbonyl compou
