86489-35-2

Upstream product

• 4457-32-3 4-nitrobenzyl chloroformate 
• 86541-23-3 (6R,7R)-2,2-dimethyl-7-(1-hydroxy-1-methylethyl)-7-isocyano-1-aza-3-oxabicyclo[4.2.0]octan-8-one 
• 86489-29-4 (6R,7S)-7-(1-Hydroxy-1-methyl-ethyl)-7-isocyano-2,2-dimethyl-3-oxa-1-aza-bicyclo[4.2.0]octan-8-one 
• 86541-72-2 (6R,7R)-7-amino-2,2-dimethyl-3-oxa-1-azabicyclo<4.2.0>octan-8-one 
• 86541-25-5 (6R,7R)-2,2-dimethyl-7-(1-hydroxy-1-methylethyl)-1-aza-3-oxabicyclo<4.2.0.>octan-8-one 
• 86489-25-0 (6R,7R)-7-benzyloxycarbonylamino-2,2-dimethyl-1-aza-3-oxabicyclo-[4.2.0]octan-8-one 
• 86489-22-7 (3R,4R)-3-benzyloxycarbonylamino-4-(2,2-dimethoxyethyl)azetidin-2-one 
• 86489-24-9 (3R,4R)-3-benzyloxycarbonylamino-4-(2-hydroxyethyl)azetidin-2-one 
• 86489-27-2 (6R,7R)-2,2-dimethyl-7-isocyano-1-aza-3-oxabicyclo[4.2.0]octan-8-one 

Downstream Products

• 86489-36-3 (3R,4R)-4-(2-hydroxyethyl)-3-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]azetidin-2-one 
• 86541-40-4 4-nitrobenzyl (2R,5R,6R)-3,7-dioxo-6-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 86541-35-7 {(2R,3R)-3-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-4-oxo-azetidin-2-yl}acetic acid 
• 86541-42-6 4-nitrobenzyl (5R,6R)-6-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-3-[2-(4-nitrobenzyloxycarbonylamino)ethylthio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 86541-41-5 4-nitrobenzyl (5R,6R)-3-(2-acetamidoethylthio)-6-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 86489-51-2 4-nitrobenzyl (5R,6R)-3-[(Z)-2-acetamidovinyl-thio]-6-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-7-oxo-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylate 
• 86541-39-1 4-nitrobenzyl 2-diazo-4-[(2R,3R)-3-{1-methyl-1-(4-nitrobenzyloxycarbonyloxy)-ethyl}-4-oxoazetidin-2-yl]-3-oxobutanoate 

Relevant academic research and scientific papers

SYNTHETIC STUDIES ON CARBAPENEM ANTIBIOTICS FROM PENICILLINS. III. STEREOSELECTIVE RADICAL REDUCTION OF A CHIRAL 3-ISOCYANOAZETIDINONE: A TOTAL SYNTHESIS OF OPTICALLY ACTIVE CARPETIMYCINS

A new, efficient synthesis of the optically active carpetimycins 1 from penicillins has been achieved via, as key steps, aldol reaction of isonitrile 19, followed by n-Bu3SnH reduction.

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof

This invention relates to novel 4-substituted-2-oxoazetidine compounds and salts thereof, which are useful intermediates in the preparation of antibiotics having the fundamental skeleton of Thienamycin, which compounds are of the formula: STR1 in which R