864971-48-2Relevant academic research and scientific papers
On the mechanism of isomerization of all-trans-retinol esters to 11-cis-retinol in retinal pigment epithelial cells: 11-Fluoro-all-trans-retinol as substrate/inhibitor in the visual cycle
Fishkin, Nathan,Yefidoff, Revital,Gollipalli, Deviprasad R.,Rando, Robert R.
, p. 5189 - 5194 (2007/10/03)
The synthesis of 11-fluoro-all-trans-retinol (11-F-tROL), which is shown to be an excellent substrate for processing by visual cycle enzymes, is described. It is isomerized to its 11-cis congener subsequent to its esterification by lecithin retinol acyl t
