864973-85-3

Upstream product

• 122051-27-8 N-(Benzyloxycarbonyl)-O-(tert-butyldiphenylsilyl)-L-serinal 
• 762-72-1 allyl-trimethyl-silane 
• 135245-97-5 methyl (2S)-3-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-[(phenylmethoxy)carbonylamino]propanoate 

Downstream Products

• 864973-90-0 (4S,5S)-5-Allyl-2,2-dimethyl-4-[(2,2,2-trifluoro-acetylamino)-methyl]-oxazolidine-3-carboxylic acid benzyl ester 
• 864973-87-5 (4S,5S)-5-Allyl-4-methanesulfonyloxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 864973-94-4 (4S,5S)-5-Allyl-4-azidomethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 864973-92-2 (4S,5S)-5-Allyl-4-hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 864973-86-4 (4S,5S)-5-Allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

A stereoselective approach to the synthesis of pseudodistomin D

A stereoselective total synthesis of the core unit of pseudodistomin D, starting from L-serine, is described. The key step is a stereoselective intramolecular Michael reaction in which the piperidine ring is formed with the obtention of 1.