86530-03-2

Upstream product

• 75321-05-0 R,S,R-3-(1'-hydroxyethyl)-2-azetidinone-4-yl acetic acid 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 19236-58-9 dibenzyl methylphosphonate 
• 86509-38-8 (3-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-oxo-propyl)-phosphonic acid dibenzyl ester 
• 185446-92-8 (3S,4R)-3-<(1R)-1-<(tert-Butyldimethylsilyl)oxy>ethyl>-4-<(methoxycarbonyl)methyl>azetidin-2-one 
• 86509-38-8 (3-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-oxo-propyl)-phosphonic acid dibenzyl ester 
• 74357-70-3 [(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-((R)-1-hydroxy-ethyl)-4-oxo-azetidin-2-yl]-acetic acid methyl ester 
• 86509-36-6 (3-{(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-oxo-propyl)-phosphonic acid dibenzyl ester 
• 74288-34-9 {(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-acetic acid methyl ester 
• 538-60-3 dibenzyl hydrogen phosphite 

Downstream Products

• 90510-08-0 Trifluoro-methanesulfonic acid (5R,6S)-2-(bis-benzyloxy-phosphoryl)-6-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-3-yl ester 
• 90497-55-5 {(5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-cyanomethylsulfanyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl}-phosphonic acid dibenzyl ester 
• 90497-60-2 C₁₇H₁₈N₂O₅PS^(1-)*K⁽¹⁺⁾ 

Relevant academic research and scientific papers

SYNTHESIS OF 3-METHYLPHOSPHONYL THIENAMYCIN AND RELATED 3-PHOSPHONYL CARBAPENEMS

The synthesis and some biological properties of the title compounds, beta-lactam antibiotic analogs, are described.

SYNTHESIS OF CARBAPENEM-3-PHOSPHONIC ACID DERIVATIVES

The synthesis of 6-(1-hydroxyethyl)-2-oxocarbapenem-3-phosphonic acid derivatives, starting from 3-iodomethyl-2-oxoazetidine is described.