86533-97-3

Upstream product

• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 86534-03-4 7-(4-Methoxyphenyl)-3-phenyl-2(5H)-oxepinon 
• 131022-59-8 3-(2,6-Dichloro-phenyl)-4-(4-methoxy-benzoylamino)-5-phenyl-4,5-dihydro-[1,2,4]oxadiazole-5-carboxylic acid 
• 131022-55-4 4-(4-Methoxy-benzoylamino)-5-phenyl-3-(2,4,6-trimethyl-phenyl)-4,5-dihydro-[1,2,4]oxadiazole-5-carboxylic acid 
• 131022-50-9 C₃₆H₃₄N₄O₅ 
• 86997-11-7 1-(4-Methoxy-phenyl)-4-phenyl-5,6,7,8,9,10-hexahydro-cycloocta[c]pyran-3-one 

Relevant academic research and scientific papers

Cyclic Alkyne Approach to Heteroatom-Containing Polycyclic Aromatic Hydrocarbon Scaffolds

We report a modular synthetic strategy for accessing heteroatom-containing polycyclic aromatic hydrocarbons (PAHs). Our approach relies on the controlled generation of transient heterocyclic alkynes and arynes. The strained intermediates undergo in situ t

Structural characterization of new 2-aryl-5-phenyl-1,3,4-oxadiazin-6-ones and their N-aroylhydrazone precursors

A series of novel 2,5-disubstituted 1,3,4-oxadiazin-6-ones and their N-aroylhydrazone precursors were synthesized and characterized by NMR and UV-Vis spectroscopy. The electronic properties of 2-aryl-5-phenyl-1,3,4-oxadiazin-6- ones are mainly dependent o

Cycloadditions of 6-Oxo-1,3,4-oxadiazines (4,5-Diaza-α-pyrones), 3. Reactions of 6-Oxo-2,5-diaryl-1,3,4-oxadiazines with Alkenes

Cycloaddition of the known 6-oxo-2,5-diphenyl-6H-1,3,4-oxadiazine (1a) and the new 2,5-diaryl derivatives 1b - g with various alkenes yield nitrogen free products.Using cyclopropenes and cyclobutene, α,β-unsaturated seven-membered enollactones 42 - 45 and the α,β-unsaturated eight-membered enollactone 47 are formed, respectively.In the presence of basic aluminum oxide 42a and d undergo a hydrogen migration to form the β,γ-unsaturated enollactones 46a and d, respectively.With other alkenes, γ-ketoketenes 33 have been observed, or are assumed to be intermediates, based on the structure of the isolated products.The six-membered eno llactones 10, 13, 15, 19, and 21 and 22 have been obtained with norbornene, norbornadiene, cyclopentene, trans-cyclooctene, and styrene.Compound 10 isomerizes to 34 on treatment with potassium tert-butoxide.The methanolyses of these enollactones result in the formation of the diastereomeric methyl esters 12 and 35.The γ-ketoketene 16 formed from trans-cyclooctene gives acid 17 and ester 18 with water and methanol, respectively.These reactions are faster than the cyclization to enollactone 19.From cis,trans-1,5-cyclooctadiene the more short-lived γ-ketoketene 40 is formed, which undergoes intramolecular cycloaddition, giving rise to the tricyclic cyclobutanone derivative 41.Tetracyclic products of type 4 are generated from benzvalene (2) and 1.The structures and configurations of compounds 10, 19, and 41 have been determined by means of X-ray analyses.