86534-24-9

Upstream product

• 86545-49-5 4(R)-acetoxy-1-<5-(benzyloxy)-2,2-dimethylpent-3(E)-en-1yl>-5-hydroxy-2-pyrrolidinone 
• 14189-99-2 (R)-(+)-2-acetoxysuccinic anhydride 
• 86534-22-7 (+)-4(R)-acetoxy-1-<5-(benzyloxy)-2,2-dimethylpent-3-(E)-en-1-yl>-2,5-pyrrolidinedione 
• 94202-33-2 (R)-2-Acetoxy-N-((E)-5-benzyloxy-2,2-dimethyl-pent-3-enyl)-succinamic acid 
• 64-18-6 formic acid 

Downstream Products

• 480-84-2 (-)-hastanecine 
• 58632-66-9 Acetic acid (1R,7S,7aS)-7-acetoxymethyl-hexahydro-pyrrolizin-1-yl ester 
• 86534-25-0 (+)-7(S)-<(benzyloxy)methyl>-1(R)-hydroxy-6(S)-(2-hydroxyprop-2-yl)-7a(R)-hexahydro-3H-pyrrolizin-3-one 

Relevant academic research and scientific papers

N-Acyliminium Ion Rearrangements: Generalities and Application to the Synthesis of Pyrrolizidine Alkaloids

N-Acyliminium ions of the 2-aza-1,5-hexadienyl type frequently rearrange to isomeric ions by a process which is formally a 2-aza-Cope rearrangement.When gem-dimethyl substitution is present at C-4 of the initially formed N-acyliminium ion, the rearranged

Enantioselective Syntheses of (-)-Hastanecine and its Enantiomer using Malic Acid as a Chiral Educt

The pyrrolizidine Base (-)-hastanecine (5) and its enantiomer (19) were prepared from R-(+) and S-(-)-malic acids, respectively.