86541-79-9

Usage

Uses

Used in Anti-Aging Applications:
Astragenol is used as an anti-aging agent for its purported ability to stimulate the production of telomerase, which helps maintain the length of telomeres. This is believed to contribute to longevity and overall health.
Used in Health and Wellness Industry:
Astragenol is used as a rejuvenating supplement for its potential antioxidant and anti-inflammatory effects, which may contribute to its anti-aging benefits and support overall health and wellness.

Upstream product

• 84680-75-1 (3β,6α,16β,20R,24S)-3-[(2,3-di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside 
• 84676-89-1 (3b,6a,16b,20R,24S)-3-((2-O-acetyl-beta-D-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside 
• 84687-47-8 acetylastragaloside I 
• 84676-88-0 isoastragaloside I 
• 86764-11-6 isoastragalosides II 
• 84605-18-5 cycloastragenol 
• 78574-94-4 cyclosieversigenin 
• 83207-58-3 astragaloside IV 

Downstream Products

• 86541-82-4 (5R,8S,10S,13R,14S,17S)-17-[(2R,5S)-5-(1-Hydroxy-1-methyl-ethyl)-2-methyl-tetrahydro-furan-2-yl]-4,4,10,13,14-pentamethyl-1,4,5,8,10,12,13,14,15,17-decahydro-2H,7H-cyclopenta[a]phenanthrene-3,6,16-trione 
• 1408236-83-8 C₂₇H₃₆O₅ 
• 1408236-84-9 C₂₆H₃₆O₇ 
• 86541-81-3 C₃₄H₅₂O₇ 
• 86568-63-0 C₃₈H₅₂F₆O₉ 
• 86500-57-4 C₃₄H₅₄O₇ 
• 86500-58-5 C₃₆H₅₆O₈ 
• 78575-00-5 3β,6α-diacetoxy-20(S),24(R)-epoxylanost-9(11)-en-16-one 
• 78575-03-8 6-acetate of 20(S),24(R)-epoxylanost-9(11)-ene-3β,6α,16β,25-tetraol 
• 78575-02-7 16-acetate of 20(S),24(R)-epoxylanost-9(11)-ene-3β,6α,16β,25-tetraol 
• 78574-99-9 3,6,16,25-tetraacetate of 20(S),24(R)-epoxylanost-9(11)-en-3β,6α,16β,25-tetraol 
• 86500-57-4 3,6-diacetate of 20(S),24(R)-epoxylanost-9(11)-en-3β,6α,16β,25-tetraol 
• 86500-58-5 3,6,16-triacetate of 20(S),24(R)-epoxylanost-9(11)-en-3β,6α,16β,25-tetraol 

Relevant academic research and scientific papers

AG-08 MOLECULE THAT IS A SAPOGENOL DERIVATIVE EXHIBITNG CYTOTOXIC EFFECTS BY ACTIVATING THE NECROSIS PATHWAY AND SYNTHESIS METHOD THEREOF

The invention is related to an AG-08 coded novel structured molecule having cytotoxic features against cancer cells. The aim of the invention is to primarily synthesize the astragenol (AG) molecule from cycloastragenol (CA) and then from here, the cytotoxic molecule coded AG-08 which enables to kill cancer cells via a pathway that is non-apoptotic as a difference from the compounds that exhibit traditional anticancer activity.

Cleavage of ring A and formation of an unusual nor-triterpene skeleton via the Baeyer-Villiger reaction

With the aim to generate a compound library for our biological screening studies, cycloastragenol was subjected to chemical transformation studies. The Baeyer-Villiger oxidation experiments provided an interesting 3,5-seco-4-nor-triterpene skeleton via ring opening followed by an unusual rearrangement. A new methodology is described for transforming triterpenoids into 3,5-seco-4-nor derivatives.

TRITERPENE GLYCOSIDES OF Astragalus AND THEIR GENINS. II. THE STRUCTURE OF CYCLOSIEVERSIGENIN

The bitter plant Astragalus sieversianus has yielded a new isoprenoid cyclosieversigenin the structure of which has been established on the basis of spectral characteristics and chemical transformations as 20(S),24(R)-epoxycycloartane-3β,6α,16β,25-tetraol.