86544-67-4Relevant academic research and scientific papers
Reactivity and Regio- and Stereo-selectivity in 1,3-Dipolar Cycloaddition of 3,4,5,6-Tetrahydro-2H-azepine 1-Oxide
Ali, Sk. Asrof,Wazeer, Mohammed I. M.
, p. 614 - 630 (2007/10/02)
A study of the regio- and stereo-chemical behaviour of the 1,3-dipolar cycloaddition of 3,4,5,6-tetrahydro-2H-azepine 1-oxide (3) with a series of alkenes has been carried out.The regio- and stereo-selectivity in these cycloadditions have been explained in terms of frontier orbital interactions, steric effects, and secondary orbital interactions.Rate constants for the cycloaddition reactions have been determined at 36 deg C.The seven-membered ring nitrone (3) is found to be more reactive than its five- or six-membered counterparts.
THE REACTION OF N-MONO AND N,N-DISUBSTITUTED HYDROXYLAMINES WITH PALLADIUM CATALYST
Murahashi, Shun-Ichi,Mitsui, Hitoshi,Watanabe, Tomonari,Zenki, Sei-ichi
, p. 1049 - 1052 (2007/10/02)
The Palladium catalyzed reactions of N,N-disubstituted and N-substituted hydroxylamines give the corresponding nitrones and azoxy compounds highly efficiently.The former reactions are performed in the presence of alkenes to give the cycloadducts which are valuable intermediates regio and stereoselectively.
