86558-23-8Relevant academic research and scientific papers
SYNTHESIS OF α-METHOXYCARBONYLAMINO-γ-ALKENYL-γ-BUTYROLACTONES-AMIDO-ALKYLATION OF DIENES WITH THE ADDUCT OF GLYOXYLIC ACID-METHYLCARBAMATE
Ben-Ishai, D.,Hirsh, S.
, p. 5441 - 5450 (1988)
Amidoalkylation of 1,3-dienes with glyoxylic acid-methyl carbamate adduct afforded α-methoxycarbonylamino-γ-alkenyl-γ-butyrolactones in 40-80 percent yield.The lactones were epoxidized to the epoxy lactones or ozonized and rearranged to γ-ketopyrrolidine-2-carboxylic acid derivatives.
AMIDOALKYLATION OF DIENES WITH ADDUCTS OF GLYOXYLIC ACID - SYNTHESIS OF α-ACYLAMINO-γ-ALKENYL-γ-BUTYROLACTONES
Ben-Ishai, D.,Hirsch, S.
, p. 955 - 958 (2007/10/02)
Amidoalkylation of 1,3-dienes with the adduct of glyoxylic acid-methyl carbamate (1) afforded α-acylamino-γ-alkenyl-γ-butyrolactones (e.g. 2, 6-9) in 40-80 percent yield and the pipecolic acid derivatives (e.g. 3) in less then 20 percent yield.An explanation is suggested to account for the above results.
