86559-75-3Relevant academic research and scientific papers
Benzotriazole-mediated alkoxyalkylation and acyloxyalkylation
Katritzky, Alan R.,Abdel-Fattah, Ashraf A.A.,Idzik, Krzysztof R.,El-Gendy, Bahaa El-Dien M.,Soloducho, Jadwiga
, p. 6477 - 6484 (2007)
Reactions of readily available and stable 1-(α-alkoxyalkyl)benzotriazoles type 9a,b and 10a-d with a variety of silyl enol ethers 11 or 1,3-dicarbonyl compounds 13 give the expected ketones 12a-l (60-92%), β-keto esters 14a,b (62-67%), and malonates 14c,d
One-Pot Three-Component Solvent-Free Cyanoaroylation of Aldehydes Using Potassium Hexacyanoferrate(II) as an Environmentally Benign Cyanide Source
Li, Zheng,Tian, Guoqiang,Ma, Yuanhong
supporting information; experimental part, p. 2164 - 2168 (2010/10/21)
An efficient method for one-pot three-component solvent-free cyanoaroylation of aldehydes using potassium hexacyanoferrate(II) as an environmentally benign cyanide source and triethylamine as a catalyst has been described. This method has advantages of not using strongly toxic cyanating agents and volatile organic solvents. In addition, the product was obtained in high yield using a simple workup procedure.
CROWN ETHER CATALYSIS IN THE SYNTHESIS OF CYANOHYDRIN DERIVATIVES
Chenevert, Robert,Plante, Raymond,Voyer, Normand
, p. 403 - 410 (2007/10/02)
Carbonyl compounds react with cyanide ion under phase transfer catalysis (18-crown-6) to give cyanohydrin anions which are trapped by acid chlorides, anhydrides or alkylating agents to give cyanohydrin derivatives.
