86562-72-3

Upstream product

• 98070-15-6 1,3-dihydroxy-3-methyl-2-butanone 
• 98-59-9 p-toluenesulfonyl chloride 
• 1756-18-9 (2RS)-2,3-dihydroxy-3-methylbutanoic acid 

Downstream Products

• 86547-26-4 Benzoesaeure-<(2S)-2,3-dihydroxy-3-methylbutyl>ester 
• 86547-27-5 Benzoesaeure-<((4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)methyl>ester 
• 1093988-29-4 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)phenyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 
• 1093988-31-8 4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzohydrazide 
• 1093988-30-7 methyl 4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzoate 
• 1093988-73-8 2-chloro-4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzohydrazide 
• 1093988-72-7 methyl 2-chloro-4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzoate 
• 1093988-66-9 2-methyl-4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzohydrazide 
• 1093988-65-8 methyl 2-methyl-4-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)benzoate 
• 1093988-32-9 3-chloro-5-[(6-chloro-3-{[5-(4-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}phenyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 
• 1094342-09-2 3-chloro-5-[(6-chloro-3-{[5-(2-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-5-methyl-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 
• 1094345-89-7 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[5-methyl-2-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-4-pyridinyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 
• 1094345-86-4 N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-5-methyl-2-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-4-pyridinecarbohydrazide 
• 1094345-84-2 N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-2-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-5-methyl-4-pyridinecarbohydrazide 

Relevant academic research and scientific papers

Synthesis of an Enantiomerically Pure Sterol Side-Chain Precursor by Enantioselective Reduction of 1,3-Dihydroxy-3-methyl-2-butanone with Baker's Yeast

1,3-Dihydroxy-3-methyl-2-butanone (1), accessible in 5 steps from 2-methyl-3-butyn-2-ol, is reduced by baker's yeast to (R)-(+)-3-methyl-1,2,3-butanetriol (2) with a high enantioselectivity.This chiral building block for the synthesis of various sterols with a modified side chain thus becomes available in 73percent yield with an enantiomeric excess of 90percent.