865626-99-9Relevant articles and documents
Palladium-catalyzed C(sp3)-H activation: A facile method for the synthesis of 3,4-dihydroquinolinone derivatives
Yan, Jia-Xuan,Li, Hu,Liu, Xiang-Wei,Shi, Jiang-Ling,Wang, Xin,Shi, Zhang-Jie
supporting information, p. 4945 - 4949 (2014/05/20)
3,4-Dihydroquinolinones were synthesized by the palladium-catalyzed, oxidative-addition-initiated activation and arylation of inert C(sp 3)-H bonds. Pd(OAc)2 and P(o-tol)3 were used as the catalyst and ligand, respectively, to improve the efficiency of the reaction. A further advantage of this reaction is that it could be performed in air. A relatively rare seven-membered palladacycle was proposed as a key intermediate of the catalytic cycle.
Novel therapeutic agents for the treatment of migraine
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Page/Page column 48-49, (2010/02/14)
The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their u