865664-04-6 Usage
Uses
Used in Pharmaceutical Synthesis:
2-chloro-3-cyclopropylpyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of novel drug molecules.
Used in Agrochemical Production:
In the agrochemical industry, 2-chloro-3-cyclopropylpyridine is used as a building block for the creation of new agrochemicals, potentially enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
2-chloro-3-cyclopropylpyridine is employed as a research compound in medicinal chemistry, aiding scientists in exploring its properties and potential uses in drug discovery and development.
It is crucial to handle 2-chloro-3-cyclopropylpyridine with care due to its classification as a hazardous material, which poses potential health and environmental risks. Its reactivity and possible toxicological effects necessitate controlled and responsible use in a laboratory or industrial setting.
Check Digit Verification of cas no
The CAS Registry Mumber 865664-04-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,5,6,6 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 865664-04:
(8*8)+(7*6)+(6*5)+(5*6)+(4*6)+(3*4)+(2*0)+(1*4)=206
206 % 10 = 6
So 865664-04-6 is a valid CAS Registry Number.
865664-04-6Relevant articles and documents
HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS
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Page/Page column 70; 72, (2015/01/16)
The present invention provides, in part, compounds of Formula (I) and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1 -mediated (or D1 -associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), age-related cognitive decline, dementia, and Parkinson's disease.
Chemoselective sp 2-sp3 cross-couplings: Iron-catalyzed alkyl transfer to dihaloaromatics
Malhotra, Sushant,Seng, Pamela S.,Koenig, Stefan G.,Deese, Alan J.,Ford, Kevin A.
supporting information, p. 3698 - 3701 (2013/08/23)
The chemoselective functionalization of a range of dihaloaromatics with methyl, cyclopropyl, and higher alkyl Grignard reagents via iron-catalyzed cross-coupling is described. The site selectivity of C-X (X = halogen) activation is determined by factors such as the position of the halogen on the ring, the solvent, and the nucleophile. A one-pot protocol for the chemoselective synthesis of mixed dialkyl heterocycles is achieved solely employing iron catalysis.
