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Usage

Uses

Used in Pharmaceutical Synthesis:
2-chloro-3-cyclopropylpyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of novel drug molecules.
Used in Agrochemical Production:
In the agrochemical industry, 2-chloro-3-cyclopropylpyridine is used as a building block for the creation of new agrochemicals, potentially enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
2-chloro-3-cyclopropylpyridine is employed as a research compound in medicinal chemistry, aiding scientists in exploring its properties and potential uses in drug discovery and development.
It is crucial to handle 2-chloro-3-cyclopropylpyridine with care due to its classification as a hazardous material, which poses potential health and environmental risks. Its reactivity and possible toxicological effects necessitate controlled and responsible use in a laboratory or industrial setting.

Upstream product

• 2402-77-9 2,3-dichloro-pyridine 
• 23719-80-4 cyclopropylmagnesium bromide 
• 78607-36-0 2-chloro-3-iodopyridine 
• 411235-57-9 cyclopropylboronic acid 

Relevant academic research and scientific papers

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula (I) and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1 -mediated (or D1 -associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), age-related cognitive decline, dementia, and Parkinson's disease.

Chemoselective sp 2-sp3 cross-couplings: Iron-catalyzed alkyl transfer to dihaloaromatics

The chemoselective functionalization of a range of dihaloaromatics with methyl, cyclopropyl, and higher alkyl Grignard reagents via iron-catalyzed cross-coupling is described. The site selectivity of C-X (X = halogen) activation is determined by factors such as the position of the halogen on the ring, the solvent, and the nucleophile. A one-pot protocol for the chemoselective synthesis of mixed dialkyl heterocycles is achieved solely employing iron catalysis.