865706-77-0

Basic information

• Product Name: 2-benzenesulfonylmethyl-5-cyclopropyl-[1,3,4]oxadiazole
• Synonyms: 2-benzenesulfonylmethyl-5-cyclopropyl-[1,3,4]oxadiazole
• CAS NO: 865706-77-0
• Molecular Weight: 264.305
• Mol File: 865706-77-0.mol

Chemical Properties

• CAS DataBase Reference: 2-benzenesulfonylmethyl-5-cyclopropyl-[1,3,4]oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzenesulfonylmethyl-5-cyclopropyl-[1,3,4]oxadiazole(865706-77-0)
• EPA Substance Registry System: 2-benzenesulfonylmethyl-5-cyclopropyl-[1,3,4]oxadiazole(865706-77-0)

Safety Data

• Hazardous Substances Data: 865706-77-0(Hazardous Substances Data)

Upstream product

• 36107-06-9 2-(phenylsulfonyl)acetohydrazide 
• 1759-53-1 cyclopropanecarboxylic acid 

Downstream Products

• 865706-78-1 C₁₇H₁₈N₂O₄S 

Relevant articles and documents

TETRAHYDROCARBAZOLES AND DERIVATIVES

The present invention relates to compounds of the formula (I) wherein R1, R2, R3, R4, R5, X1, X2, X3, X4, n, and k are defined in the description and claims, and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for in the treatment and prophylaxis of diseases which are modulated by LXRα and/or LXR? agonists, including increased lipid and cholesterol levels, particularly low HDL-cholesterol, high LDL-cholesterol, atherosclerotic diseases, diabetes, particularly non-insulin dependent diabetes mellitus, metabolic syndrome, dyslipidemia, Alzheimer's disease, sepsis, inflammatory diseases such as colitis, pancreatitis, cholestasis/fibrosis of the liver, and diseases that have an inflammatory component such as Alzheimer's disease or impaired/improvable cognitive function.