865838-18-2Relevant academic research and scientific papers
Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and – pyrimidines
Yoon, Ji-seong,Jarhad, Dnyandev B.,Kim, Gyudong,Nayak, Akshata,Zhao, Long Xuan,Yu, Jinha,Kim, Hong-Rae,Lee, Ji Yun,Mulamoottil, Varughese A.,Chandra, Girish,Byun, Woong Sub,Lee, Sang Kook,Kim, Yong-Chul,Jeong, Lak Shin
, p. 406 - 417 (2018/06/26)
Based on the potent anticancer activity of 6′-fluorocyclopentenyl-cytosine 2b in phase IIa clinical trials for the treatment of gemcitabine-resistant pancreatic cancer, we carried out a systematic structure-activity relationship study of 6′-fluorocyclopen
Nucleoside derivatives and therapeutic uses therof
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Page/Page column 8, (2010/02/14)
The present invention relates to nucleoside derivatives represented by general formulas I and II, their synthetic methods and their pharmacologically acceptable salts thereof, and compositions containing such compounds. Methods for treating hyperprolifera
