865838-65-9Relevant academic research and scientific papers
Synthesis of chiral ansa-bridged macrocyclic lactams ([16]metacyclophanes) related to geldanamycin
Lemarchand, Aude,Bach, Thorsten
, p. 1977 - 1990 (2007/10/03)
Two chiral ansa-bridged lactams ([16]metacyclophanes) 2a,b were synthesized starting from 2-methoxyhydroquinone diisopropyl ether (6) in 14 (2a, 3.9% overall) and 16 synthetic steps (2b, 0.6% overall). Both compounds contain typical features of geldanamyc
