865855-24-9Relevant academic research and scientific papers
Synthesis and anti-inflammatory activity evaluation of unsymmetrical selenides
Martinez-Ramos, Federico,Salgado-Zamora, Hector,Campos-Aldrete, Maria Elena,Melendez-Camargo, Estela,Marquez-Flores, Yazmin,Soriano-Garcia, Manuel
, p. 1432 - 1437 (2008/09/21)
The alkylation reaction of 2,2′-diseleno and 4,4′-diseleno-bis(benzoic acid) derivatives in the presence of sodium borohydride and alkyl halides allowed the synthesis of various new o- and p-alkylselenenylated benzoic acid derivatives in good yields. The anti-inflammatory activity of selected selenide derivatives on granuloma induced by subcutaneous implantation of cotton pellets in Wistar rats was examined. Selenium derivatives 2a, 2c and 2e showed anti-inflammatory activity although to a lesser extent as compared to indomethacin, however they were found less toxic than the latter.
GLUTATHIONE PEROXIDASE MIMETICS AND USES THEREOF
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Page/Page column 29-30; Sheet 1/5, (2010/11/27)
This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidativ
Aromatic derivatives and tellurium analogues of cyclic seleninate esters and spirodioxyselenuranes that act as glutathione peroxidase mimetics
Back, Thomas G.,Kuzma, Dusan,Parvez, Masood
, p. 9230 - 9236 (2007/10/03)
Several novel organoselenium and tellurium compounds were prepared and evaluated as mimetics of the selenoenzyme glutathione peroxidase, which protects cells from oxidative stress by reducing harmful peroxides with the thiol glutathione. The compounds wer
