866030-97-9

Basic information

• Product Name: (2S,3S,4R)-3,4-di-O-benzyl-2-docosanoylamino-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol
• Synonyms: (2S,3S,4R)-3,4-di-O-benzyl-2-docosanoylamino-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol
• CAS NO: 866030-97-9
• Molecular Weight: 1254.84
• Mol File: 866030-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,4R)-3,4-di-O-benzyl-2-docosanoylamino-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4R)-3,4-di-O-benzyl-2-docosanoylamino-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol(866030-97-9)
• EPA Substance Registry System: (2S,3S,4R)-3,4-di-O-benzyl-2-docosanoylamino-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol(866030-97-9)

Safety Data

• Hazardous Substances Data: 866030-97-9(Hazardous Substances Data)

Upstream product

• 21193-75-9 D-galactal 
• 100-39-0 benzyl bromide 
• 80040-79-5 3,4,6-tri-O-benzyl-D-galactal 
• 112-85-6 n-docosanoic acid 
• 1054682-27-7 (2S,3S,4R)-2-azido-3,4-di-O-benzyl-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol 
• 866030-91-3 3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl acetate 
• 866030-92-4 3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl fluoride 
• 866030-96-8 (2S,3S,4R)-2-amino-3,4-di-O-benzyl-1-O-(3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-α-D-galactopyranosyl)-1,3,4-octadecanetriol 
• 21132-76-3 docosanoyl chloride 

Relevant articles and documents

Immunomodulatory α-galactoglycosphingolipids: Synthesis of 2′-fluoro-2′-deoxy-α-galactosylceramide and an evaluation of its immunostimulating properties

In the framework of a project to assess the immunomodulating properties of α-galactosyl glycosphingolipids, the total synthesis of 1-O-(2-fluoro-2-deoxy-α-D-galactopyranosyl)-2-docosanoylamino-1,3, 4-octadecanetriol (1), a 2′-fluoro analogue of the immunostimulating α-galactoglycosphingolipids, was accomplished. The glycosidation reaction of the azido precursor of sphingosine was performed using the Mukaiyama glycosidation reaction. The stimulation of mouse splenocyte proliferation by the 2′-fluoro analogue was highly reduced compared to that of the α-galactoglycosphingolipids, thereby confirming that a free galactose 2-OH group is essential for the immunostimulatory activity. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.