866124-50-7Relevant academic research and scientific papers
Discovery of hydroxamic acid analogs as dual inhibitors of phosphodiesterase-1 and -5
Dan, Akihito,Shiyama, Takaaki,Yamazaki, Kazuto,Kusunose, Naoto,Fujita, Katsuya,Sato, Hideshi,Matsui, Kazutaka,Kitano, Masafumi
, p. 4085 - 4090 (2007/10/03)
HTS and the following synthesis of a series of the compounds led us to the discovery of hydroxamic acid analogs as potent dual inhibitors of phosphodiesterase (PDE)-1 and 5. These compounds have highly related structure and deviation of the structure usua
