866138-79-6

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 197229-91-7 (2S)-5-{[(tert-butyl)(dimethyl)silyl]oxy}pentane-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 127154-84-1 tert-butylpent-4-enyloxydimethylsilane 
• 821-09-0 n-Pent-4-enyl alcohol 
• 58879-34-8 (S)-5-tosyloxypentan-4-olide 
• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 
• 89872-57-1 (2S)-2,5-dihydroxy-1-tosyloxypentane 

Downstream Products

• 866138-82-1 (4S,6E)-4-(tert-butyldiphenylsilyloxy)oct-6-enal 
• 866138-81-0 (4S,6E)-4-tert-butyldiphenylsilyloxy-6-octen-1-ol 
• 866138-92-3 (4S,6E)-1-tert-butyldimethylsilyloxy-4-tert-butyldiphenylsilyloxy-6-octene 
• 866138-95-6 ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate 
• 866138-97-8 ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-((2-pyridylselenyl)methyl)tetradeca-2,12-dienoate 
• 866138-98-9 (2E,12E)-(4R,6R,7S,10S)-4-(tert-Butyl-dimethyl-silanyloxy)-10-(tert-butyl-diphenyl-silanyloxy)-7-methanesulfonyloxy-6-(pyridin-2-ylselanylmethyl)-tetradeca-2,12-dienoic acid ethyl ester 
• 866138-87-6 ethyl (2E,4R,6R,7S,10S,12E)-6-((R)-4-benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxytetradeca-2,12-dienoate 
• 866138-88-7 ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(trityloxymethyl)tetradeca-2,12-dienoate 
• 866138-96-7 ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-(methanesulfonyloxy)-6-(trityloxymethyl)tetradeca-2,12-dienoate 
• 1229358-49-9 (S)-{[4-(benzyloxy)hept-6-en-1-yl]oxy}(tert-butyl)(dimethyl)silane 
• 1229358-52-4 (4S)-4-(benzyloxy)hept-6-en-1-ol 
• 1229358-29-5 (4S)-4-(benzyloxy)hept-6-enoic acid 
• 1229358-24-0 (2R,3R)-3-(benzyloxy)pent-4-en-2-yl (4S)-4-(benzyloxy)hept-6-enoate 
• 1229358-55-7 (5S,7Z,9R,10R)-5,9-bis(benzyloxy)-10-methyl-3,4,5,6,9,10-hexahydro-2H-oxecin-2-one 

Relevant academic research and scientific papers

Asymmetric total synthesis of stagonolide G

A simple asymmetric total synthesis of stagonolide G (1) is described. Asymmetric dihydroxylation, regioselective epoxide ring opening, and vinyl Grignard reactions are involved in generating the stereogenic centers C(4) and C(8), followed by Grubbs-II-ca

Synthesis of (-)-amphidinolide K fragment C9-C22

(Chemical Equation Presented) The key fragment (2a or 2b) in a total synthesis of the cytotoxic macrolide (-)-amphidinolide K (1) has been achieved from synthons C9-C14 (3) and C15-C22 (4), which have both been prepared from glutamic acid in good overall yields.