86618-04-4Relevant academic research and scientific papers
A NEW CONVENIENT SYNTHESIS OF α-ARYLPROPIONIC ACID ESTERS AND α-ARYLPROPIONITRILES
Amano, Takehiro,Yoshikawa, Kensei,Sano, Tatsuhiko,Ohuchi, Yutaka,Shiono, Manzo,et al.
, p. 499 - 508 (2007/10/02)
Various types of α-arylpropionic acid esters were effectively obtained by the coupling reaction of aryl Grignard reagents and α-bromopropionic acid esters in the presence of nickel catalysts. α-Arylpropionitriles, precursors of α-arylpropionic acids, were also synthesized by the reaction of α-methanesulfonyloxypropionitrile and arylcopper reagents prepared from equimolar amount of arylmagnesium halides and copper(I) bromide.
