23853-76-1

Usage

Functional groups

Chloro-substituted aromatic compound, butenyl side chain

Common uses

a. Organic synthesis
b. Building block for various organic compounds
c. Production of fragrances and flavor compounds

Physical state

Colorless liquid

Odor

Strong aromatic

Flammability

Flammable under certain conditions

Safety precautions

Handle with caution, follow proper safety protocols in laboratory or industrial settings

Upstream product

• 503-60-6 3,3-dimethyl-allyl chloride 
• 51833-36-4 4-chlorophenylmagnesium chloride 
• 4251-65-4 (4-chlorophenyl)acetaldehyde 
• 24470-78-8 isopropyltriphenylphosphonium iodide 
• 106-46-7 para-dichlorobenzene 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 106-39-8 bromochlorobenzene 

Downstream Products

• 86618-04-4 2-[4-(3-Methyl-but-2-enyl)-phenyl]-propionic acid tert-butyl ester 
• 91802-65-2 1-(4-chlorophenyl)-3-formamido-3-methylbutane 
• 77745-81-4 4-<(4-Chlorphenyl)methyl>-5,5-dimethyl-2-oxo-3-imidazolin-3-oxid 
• 77745-78-9 (E)-3-Amino-1-(4-chlorphenyl)-3-methyl-2-butanon-oxim 
• 64451-77-0 2-<(4-(3-methylbutyl)phenyl)>propionic acid 
• 73318-89-5 α-(p-prenylphenyl)propionic acid 
• 106364-41-4 p-(3-methyl-2-butenyl)phenyl magnesium chloride 
• 85475-56-5 ethyl 2-<(4-(3-methyl-2-butenyl)phenyl)>propionate 
• 77745-75-6 2,2'-Dichlor-1,1'-bis<(4-chlorphenyl)methyl>-2,2'-dimethylazopropan-N,N'-dioxid 
• 23853-86-3 2-[4-(3-Methyl-but-2-enyl)-phenyl]-propan-2-ol 

Relevant academic research and scientific papers

Synthesis of Tetrahydroisoindolinones via a Metal-Free Dehydrogenative Diels-Alder Reaction

A metal-free dehydrogenative Diels-Alder reaction of substituted alkenes for the synthesis of tetrahydroisoindolinones has been exploited for the first time. This new method features functional group tolerance and broad substrate scope, providing an efficient access to biologically active tetrahydroisoindolinone skeletons with endo steroselectivity in good to excellent yields. (Figure presented.).

Metal-Free Dehydrogenative Diels-Alder Reactions of Prenyl Derivatives with Dienophiles via a Thermal Reversible Process

An efficient dehydrogenative Diels-Alder reaction of prenyl derivatives with dienophiles has been developed. The reaction exhibits broad substrate scope and provides efficient access to cyclohexene derivatives with good to excellent yields. A reasonable mechanism involving a metal-free thermal reversible process is proposed.

Synthesis of benzazepine-based nitrones as radical traps

Benzazepine-based nitrones have been synthesized utilizing a modified Bischler-Napieralski reaction as the key step. These compounds are cyclic analogs of the radical trap phenyl t-butyl nitrone.

Effective Synthesis of 2-propionic Acid via Hydromagnesation Reaction with Nickel or Titanium Catalysts

2-propionic acid was synthesized in 82percent yield via nickel(II) chloride or dichlorobis5-cyclopentadienyl>titanium-catalyzed hydromagnesation of 1-(3-methyl-2-butenyl)-4-vinylbenzene obtained in ca. 63-68percent yield by the coupling reaction of 4-(3-methyl-2-butenyl)phenylmagnesium chloride with vinyl chloride.

Process for producing 1-(p-prenylphenyl)ethanol

A process for producing 1-(p-prenylphenyl)ethanol, which comprises reacting p-chloroprenylbenzene with magnesium at a temperature between 100° C. and 150° C. to form a Grignard reagent, and then reacting it with acetaldehyde.