866181-59-1Relevant articles and documents
A NHC-Involved, cascade, metal-free, and three-component synthesis of 2,3-diarylated fully substituted furans under solvent-free conditions
Yu, Chenxia,Lu, Jun,Li, Tuanjie,Wang, Donglin,Qin, Binbin,Zhang, Honghong,Yao, Changsheng
, p. 2420 - 2424 (2011/11/05)
An efficient synthesis of 2,3-diarylated fully substituted furans was performed through the sequential reactions of Knoevenagel reaction, Stetter reaction catalyzed by NHC, and intramolecular cyclization under solvent-free conditions. The protocol has the
An Efficient synthesis of 2-aminofuran-3-carbonitriles via cascade Stetter-γ-ketonitrile cyclization reaction catalyzed by N-heterocyclic carbene
Liu, Peng,Lei, Min,Ma, Lei,Hu, Lihong
supporting information; experimental part, p. 1133 - 1136 (2011/06/24)
An efficient method for the synthesis of 4,5-disubstituted 2-aminofuran-3-carbonitriles via a cascade Stetter-γ-ketonitrile cyclization reaction of aromatic aldehydes with acylidenemalononitriles, catalyzed by N-heterocyclic carbenes, has been developed.
COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN
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Page/Page column 34-36, (2010/02/14)
A new furopyrimidine compound, their pharmaceutically acceptable salt, and a tyrosine kinase activity inhibitor. The furopyrimidine compound is a compound defined by chemical formula 1, 2, 3 or 4, on their precursor, and can exist as a form of free base or in an acid-addition salt. Since the furopyrimidine compound has an effect of inhibiting activity of DDR2 tyrosine kinase, it can be used in treating illnesses caused by the DDR2 tyrosine kinase activity such as hepatocirrhosis, rheumatoid arthritis or cancer.