866217-86-9Relevant academic research and scientific papers
Rational design of new bifunctional inhibitors of type II dehydroquinase
Toscano, Miguel D.,Stewart, Kirsty A.,Coggins, John R.,Lapthorn, Adrian J.,Abell, Chris
, p. 3102 - 3104 (2007/10/03)
Selective inhibitors of type II dehydroquinase were rationally designed to explore a second binding-pocket in the active-site. The molecular modelling, synthesis, inhibition studies and crystal structure determination are described. The Royal Society of C
