86632-66-8Relevant articles and documents
Design of anticandidal agents: Synthesis and biological properties of analogues of polyoxin L
Shenbagamurthi,Smith,Becker,Steinfeld,Naider
, p. 1518 - 1522 (2007/10/02)
Six analogues of polyoxin L were synthesized from uridine. All of these analogues inhibited chitin synthetase from Candida albicans. Derivatization of the amine terminus of the polyoxin analogues resulted in loss of activity, and analogues containing arom