866412-74-0

Upstream product

• 872458-59-8 11-O-methanesulfonylreserpic acid lactone 
• 866412-75-1 11-O-p-toluenesulfonylreserpic acid lactone 

Downstream Products

• 866412-75-1 11-O-p-toluenesulfonylreserpic acid lactone 
• 1535202-89-1 methyl (1R,15S,17R,18R,19S,20S)-6-{[(tert-butoxy)carbonyl]oxy}-17-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxyphenyl}carbonyloxy)-18-methoxy-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2⁽¹⁰⁾,4,6,8-tetraene-19-carboxylate 
• 1535202-90-4 methyl (1R,15S,17R,18R,19S,20S)-17-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxyphenyl}carbonyloxy)-6-hydroxy-18-methoxy-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2⁽¹⁰⁾,4,6,8-tetraene-19-carboxylate 
• 1535202-91-5 methyl (1R,15S,17R,18R,19S,20S)-6-(acetyloxy)-17-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxyphenyl}carbonyloxy)-18-methoxy-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2⁽¹⁰⁾,4,6,8-tetraene-19-carboxylate 
• 1535202-92-6 methyl (1R,15S,17R,18R,19S,20S)-6-(benzoyloxy)-17-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxyphenyl}carbonyloxy)-18-methoxy-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2⁽¹⁰⁾,4,6,8-tetraene-19-carboxylate 
• 1535203-29-2 methyl (1R,15S,17R,18R,19S,20S)-6-[(2-{[(tertbutoxy)carbonyl]amino}acetyl)oxy]-17-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxyphenyl}carbonyloxy)-18-methoxy-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2⁽¹⁰⁾,4,6,8-tetraene-19-carboxylate 

Relevant academic research and scientific papers

Synthesis of deserpidine from reserpine

The Rauwolfia alkaloids reserpine (1) and deserpidine (2), two alkaloids from Rauwolfia species, have been widely used for their antihypertensive action. Deserpidine (2) is a compound with limited availability from natural sources, and its synthesis from 1 in six steps (41% overall yield) is reported here.