86647-53-2

Upstream product

• 27356-87-2 ethyl 2-phenethylpropenoate 
• 75-44-5 phosgene 
• 71158-24-2 N-Methyl-N-(2-carboethoxy-4-phenylbutyl)amine 

Downstream Products

• 84524-32-3 (S)-2-[(2-Ethoxycarbonyl-4-phenyl-butyl)-methyl-carbamoyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid 
• 86642-41-3 (S)-2-[(2-Carboxy-4-phenyl-butyl)-methyl-carbamoyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid 
• 84515-12-8 (S)-2-[(2-Ethoxycarbonyl-4-phenyl-butyl)-methyl-carbamoyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives

1-(Carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives of the formula STR1 where each R1 is independently alkyl, alkoxy, acyloxy, hydroxy, halo or trifluoromethyl, n is 0, 1, 2 or 3, R2 and R3 are independently hydroxy, alkoxy, amino or substituted amino, R4 and R5 are independently hydrogen, alkyl or substituted alkyl, R6 is hydrogen, alkyl or substituted alkyl, and Y is O, S or N--R7 where R7 is hydrogen, alkyl, cyano or substituted alkyl, and salts thereof, which are useful as antihypertensive and cardioactive agents, methods of preparing the same, and pharmaceutical compositions thereof, are provided.