866472-42-6 Usage
Description
6-Amino-indan-1-ol, with the molecular formula C9H11NO, is a white to off-white crystalline solid that exhibits solubility in both water and organic solvents. This chemical compound is recognized for its versatile reactivity, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, dyes, and pigments. Its potential applications extend to medicinal chemistry, where it serves as a chiral building block for creating biologically active molecules, and it has been investigated for its neuroprotective and antioxidant properties.
Uses
Used in Pharmaceutical Synthesis:
6-Amino-indan-1-ol is utilized as a key intermediate in the synthesis of various pharmaceuticals due to its ability to react with a wide range of chemical groups, contributing to the development of new drugs with diverse therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 6-Amino-indan-1-ol serves as a building block for the creation of compounds with pesticidal properties, enhancing crop protection and contributing to increased agricultural productivity.
Used in Organic Synthesis:
6-Amino-indan-1-ol is employed as a versatile building block in organic synthesis, allowing for the construction of complex organic molecules with potential applications in various fields, including materials science and specialty chemicals.
Used in Dye and Pigment Manufacturing:
6-AMINO-INDAN-1-OL is used as a reagent in the production of dyes and pigments, contributing to the coloration and performance characteristics of these products in various industries such as textiles, plastics, and inks.
Used in Medicinal Chemistry:
6-Amino-indan-1-ol is applied as a chiral building block in medicinal chemistry, enabling the synthesis of enantiomerically pure compounds with improved pharmacological properties and reduced side effects.
Used in Neuroprotective and Antioxidant Research:
6-Amino-indan-1-ol has been studied for its potential neuroprotective and antioxidant properties, indicating its possible use in the development of therapeutic agents for neurological disorders and conditions associated with oxidative stress.
Check Digit Verification of cas no
The CAS Registry Mumber 866472-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,4,7 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 866472-42:
(8*8)+(7*6)+(6*6)+(5*4)+(4*7)+(3*2)+(2*4)+(1*2)=206
206 % 10 = 6
So 866472-42-6 is a valid CAS Registry Number.
866472-42-6Relevant articles and documents
M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: Serominic compounds
Suckling, Colin J.,Murphy, John A.,Khalaf, Abedawn I.,Zhou, Sheng-ze,Lizos, Dimitris E.,van Nhien, Albert Nguyen,Yasumatsu, Hiroshi,McVie, Allan,Young, Louise C.,McCraw, Corinna,Waterman, Peter G.,Morris, Brian J.,Pratt, Judith A.,Harvey, Alan L.
, p. 2649 - 2655 (2008/02/02)
Chronic low-dose treatment of rats with the psychomimetic drug, phencyclidine, induces regionally specific metabolic and neurochemical changes in the CNS that mirror those observed in the brains of schizophrenic patients. Recent evidence suggests that drugs targeting serotoninergic and muscarinic receptors, and in particular 5-HT7 antagonists and M4 agonists, exert beneficial effects in this model of schizophrenia. Compounds that display this combined pattern of activity we refer to as serominic compounds. Based upon leads from natural product screening, we have designed and synthesised such serominic compounds, which are principally arylamidine derivatives of tetrahydroisoquinolines, and shown that they have the required serominic profile in ligand binding assays and show potential antipsychotic activity in functional assays.
