866535-48-0

Upstream product

• 289472-23-7 2,6-bis(methoxymethyloxy)-4-(2-phenylethyl)benzaldehyde 
• 78916-50-4 1,3-dimethoxy-5-(2-phenylethyl)benzene 
• 289472-21-5 2,6-dihydroxy-4-phenethyl-benzaldehyde 
• 289472-07-7 2,6-dimethoxy-4-(2-phenylethyl)benzaldehyde 

Downstream Products

• 289472-27-1 2-[(Z)-4-(2,6-Bis-methoxymethoxy-4-phenethyl-phenyl)-2-methyl-but-2-enyloxy]-tetrahydro-pyran 
• 289472-12-4 2-((Z)-4-Hydroxy-3-methyl-but-2-enyl)-5-phenethyl-benzene-1,3-diol 
• 68104-12-1 3-methyl-8-(2-phenylethyl)-2,5-dihydro-1-benzoxepin-6-ol 
• 289472-25-9 2-Bromomethyl-1,3-bis-methoxymethoxy-5-phenethyl-benzene 

Relevant academic research and scientific papers

Synthesis of two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids

Two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids, 6-hydroxy-3-methyl-8-(phenylethyl)-2,5-dihydro-1-benzoxepin-9-carboxylic acid (radulanin E) (1) and 9-hydroxy-3-methyl-2,5-dihydro-1-benzoxepin-7-carboxylic acid (2), were synthes

A new preparation of 2,5-dihydro-1-benzoxepins using Mitsunobu cyclization, and the synthesis of natural radulanins

Mitsunobu cyclization of o-[4-hydroxy-3-methyl-2(Z)-butenyl]phenol 2a effected selective seven-membered cyclization to give 3-methyl-2,5-dihydro-1- benoxepin 1a. Using this procedure, natural radulanin A and radulanin A methyl ether were synthesized effec