866535-71-9Relevant academic research and scientific papers
Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group
Ivanova, Olga A.,Andronov, Vladimir A.,Vasin, Vladimir S.,Shumsky, Alexey N.,Rybakov, Victor B.,Voskressensky, Leonid G.,Trushkov, Igor V.
supporting information, p. 7947 - 7952 (2019/01/04)
Lewis-acid-induced domino transformations of donor-acceptor cyclopropanes, possessing a nucleophilic center embedded in a donor group, into functionalized 2,3-dihydrobenzo[b]furans and 2,3-dihydrobenzo[b]thiophenes are reported herein. An unusual switch o
Synthesis of Benzodioxane and Benzofuran Scaffolds Found in Neolignans via TMS Triflate Mediated Addition to 1,4-Benzodioxane Hemiacetals
Jung, Eun-Kyung,Pilkington, Lisa I.,Barker, David
, p. 1190 - 1205 (2017/03/11)
This research reports the successful asymmetric synthesis of both a 9-hydroxy-5′-methoxy-1,4-benzodioxane framework and a highly functionalised benzofuran scaffold. Both synthetically desirable structures are the result of a Lewis acid catalysed addition
DMAP promoted tandem addition reactions forming substituted tetrahydroxanthones
Castillo-Contreras, Emmanuel B.,Dake, Gregory R.
supporting information, p. 1642 - 1645 (2014/04/17)
Substituted tetrahydroxanthones are constructed using a DMAP-promoted tandem nucleophilic addition process. The reaction yields range from 39% to 73%. Disubstituted tetrahydroxanthones are generated as a -2.3:1 mixture of diastereomers favoring the format
Asymmetric synthesis and CD investigation of the 1,4-benzodioxane lignans eusiderins A, B, C, G, L, and M
Pilkington, Lisa I.,Barker, David
, p. 8156 - 8166,11 (2020/10/15)
The enantioselective synthesis of (-)-eusiderins A (1), B (2), G (25), L (23), M (5) and (+)-eusiderin C (20) and a range of analogues was undertaken using an efficient, divergent synthesis all from a single chiral aldehyde 15, which was derived from (S)-
Synthesis of two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids
Yamaguchi, Seiji,Tsuchida, Nao,Miyazawa, Masahiro,Hirai, Yoshiro
, p. 7505 - 7511 (2007/10/03)
Two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids, 6-hydroxy-3-methyl-8-(phenylethyl)-2,5-dihydro-1-benzoxepin-9-carboxylic acid (radulanin E) (1) and 9-hydroxy-3-methyl-2,5-dihydro-1-benzoxepin-7-carboxylic acid (2), were synthes
