866621-25-2Relevant academic research and scientific papers
Histone Deacetylase Inhibitors
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Paragraph 0480, (2013/12/04)
This invention relates to generally inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3).
HISTONE DEACETYLASE INHIBITORS
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Page/Page column 107-108, (2012/09/21)
This invention relates to generally inhibiting histone deacetylase (HDAC) enzymes (e.g., HDAC1, HDAC2, and HDAC3).
A preparative route to methyl 3-(heteroaryl)acrylates using Heck methodology
Kwok, Thomas J.,Virgilio, Joseph A.
, p. 694 - 696 (2012/12/25)
Methyl 3-(heteroaryl)acrylates were prepared using Heck coupling of heteroarene halides with methyl acrylate mediated by Pd(OAc)2/ P(OCH3)3. Reactions were highly efficient (reaction times between 60 and 120 min) and scalable to 100 g of heteroarene halide. The isolated yields are from 76 to 99%.
