866641-17-0

Upstream product

• 866640-84-8 ethyl 2-(4-{[(2-tert-butoxy-2-oxoethyl)amino]methyl}-2,6-dimethylphenoxy)-2-methylpropanoate 
• 137090-44-9 [5-Methyl-2-(4-methylphenyl)-4-oxazolyl]methyl Chloride 
• 866640-85-9 ethyl 2-[4-({(2-tert-butoxy-2-oxoethyl)[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)-2,6-dimethylphenoxy]-2-methylpropanoate 

Downstream Products

• 866641-18-1 2-[4-[[carboxymethyl-(5-methyl-2-p-tolyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of 2-aminoacetamide derivatives as peroxisome proliferator-activated receptor α/γ dual agonists

We describe the design, syntheses, and structure-activity relationships of novel zwitterionic compounds as nonthiazolidinedion-based peroxisome proliferator-activated receptor (PPAR) α/γ dual agonists. In our previous report, we obtained compound 1 showin

PHENOXYACETIC ACID DERIVATIVES AND DRUGS USING THE SAME

It is intended to provide a novel compound having an excellent agonism to PPARs α/γ and desirable properties as a drug. An agonist to peroxisome proliferator-activated receptors α/γ which is represented by the general formula (I) (wherein Q represents an optionally substituted benzene ring or pyridine ring; R1 and R2 represent each an optionally substituted phenyl group or a 5- to 6-membered aromatic heterocycle group; X, Y and Z independently represent each C, O, S or N; R3 to R9 represent each a hydrogen atom, a lower alkyl group, etc.; and n is an integer of from 0 to 3.

PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME

Novel compounds having excellent PPAR α/γ agonist effects and having desirable properties for medicaments are provided. Peroxisome proliferator-activated receptor α/γ agonists of the general formula (I): (wherein Q is an optionally-substituted benzene or