866789-01-7Relevant academic research and scientific papers
A phase-switch purification approach for the expedient removal of tagged reagents and scavengers following their application in organic synthesis
Siu, Jason,Baxendale, Ian R.,Lewthwaite, Russell A.,Ley, Steven V.
, p. 3140 - 3160 (2005)
In this paper we wish to report on a variety of expedient chemical transformations and purifications achieved via a generic 'catch and release' methodology, based on a synthetically inert bipyridyl chelating tag that can be selectively captured with a resin-bound copper(II) species. Utilising this approach we are able to derive many of the same benefits associated with both solid phase synthesis and supported reagent methods. The Royal Society of Chemistry 2005.
