866849-00-5 Usage
Uses
Used in Pharmaceutical Industry:
(2',3'-dihydrospiro[[1,3]dioxolane-2,1'-indene]-6'-yl)methanol is used as a reagent for the development of novel pharmaceuticals and biologically active compounds. Its unique properties and versatility in chemical synthesis make it a promising building block for creating various derivatives with different properties and potential applications.
Used in Organic Synthesis:
(2',3'-dihydrospiro[[1,3]dioxolane-2,1'-indene]-6'-yl)methanol is used as a reagent in organic synthesis for its potential to undergo diverse chemical reactions. This allows researchers to modify the compound and create derivatives with different properties, expanding its range of applications in various fields.
Used in Medicinal Chemistry Research:
(2',3'-dihydrospiro[[1,3]dioxolane-2,1'-indene]-6'-yl)methanol is used as a reagent in medicinal chemistry research to explore its potential applications in the development of new drugs and therapies. Its unique properties and ability to be modified make it a valuable tool for researchers working on innovative pharmaceutical solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 866849-00-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,8,4 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 866849-00:
(8*8)+(7*6)+(6*6)+(5*8)+(4*4)+(3*9)+(2*0)+(1*0)=225
225 % 10 = 5
So 866849-00-5 is a valid CAS Registry Number.
866849-00-5Relevant academic research and scientific papers
Hit-to-lead optimization of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of KDR kinase inhibitors
Dinges, Juergen,Akritopoulou-Zanze, Irini,Arnold, Lee D.,Barlozzari, Teresa,Bousquet, Peter F.,Cunha, George A.,Ericsson, Anna M.,Iwasaki, Nobuhiko,Michaelides, Michael R.,Ogawa, Nobuo,Phelan, Kathleen M.,Rafferty, Paul,Sowin, Thomas J.,Stewart, Kent D.,Tokuyama, Ryukou,Xia, Zhiren,Zhang, Henry Q.
, p. 4371 - 4375 (2007/10/03)
A series of 1,4-dihydroindeno[1,2-c]pyrazoles was prepared and evaluated for their enzymatic inhibition of KDR kinase. Computer modeling studies revealed the importance of attaching a basic side chain in predicting the binding mode of those compounds. Fur
TRICYCLIC PYRAZOLE KINASE INHIBITORS
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Page/Page column 61, (2008/06/13)
Compounds of the present invention are useful for inhibiting protein tyrosine kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
