866852-05-3Relevant academic research and scientific papers
1,4-Dihydroindeno[1,2-c]pyrazoles as novel multitargeted receptor tyrosine kinase inhibitors
Dinges, Jürgen,Ashworth, Kimba L.,Akritopolou-Zanze, Irini,Arnold, Lee D.,Baumeister, Steven A.,Bousquet, Peter F.,Cunha, George A.,Davidsen, Steven K.,Djuric, Stevan W.,Gracias, Vijaya J.,Michaelides, Michael R.,Rafferty, Paul,Sowin, Thomas J.,Stewart, Kent D.,Xia, Zhiren,Zhang, Henry Q.
, p. 4266 - 4271 (2006)
A series of 1,4-dihydroindeno[1,2-c]pyrazoles with a 3-thiophene substituent carrying a urea-type side chain were identified as potent multitargeted (VEGFR and PDGFR families) receptor tyrosine kinase inhibitors. A KDR homology model suggested that the ur
