86688-96-2

Basic information

• Product Name: (PYRROL-3-YL)-ACETIC ACID
• Synonyms: (PYRROL-3-YL)-ACETIC ACID ;1H-Pyrrole-3-aceticacid(9CI);(1H-Pyrrol-3-yl)-acetic acid;1H-Pyrrole-3-acetic acid;2-(1H-Pyrrol-3-yl)acetic acid
• CAS NO: 86688-96-2
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.12528
• Product Categories: PYRROLE
• Mol File: 86688-96-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 90-91 °C
• Boiling Point: 312.3°C at 760 mmHg
• Flash Point: 142.7°C
• Appearance: /
• Density: 1.314g/cm³
• Vapor Pressure: 0.000228mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: 2-8°C
• PKA: 4.42±0.10(Predicted)
• CAS DataBase Reference: (PYRROL-3-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (PYRROL-3-YL)-ACETIC ACID(86688-96-2)
• EPA Substance Registry System: (PYRROL-3-YL)-ACETIC ACID(86688-96-2)

Safety Data

• Hazardous Substances Data: 86688-96-2(Hazardous Substances Data)

Usage

General Description

(PYRROL-3-YL)-ACETIC ACID, also known as 3-pyrrolylacetic acid, is a chemical compound with the molecular formula C7H7NO2. It is a derivative of pyrrole, a five-membered aromatic heterocycle, and acetic acid. (PYRROL-3-YL)-ACETIC ACID is commonly used in organic synthesis and pharmaceutical research due to its potential therapeutic properties. It has been studied for its potential as an anti-inflammatory agent and for its ability to inhibit the growth of cancer cells. Additionally, (PYRROL-3-YL)-ACETIC ACID has been investigated for its potential application in the treatment of neurological disorders. Its unique structure and properties make it an interesting and valuable chemical for various scientific and industrial applications.

InChI:InChI=1/C6H7NO2/c8-6(9)3-5-1-2-7-4-5/h1-2,4,7H,3H2,(H,8,9)

Upstream product

• 87630-41-9 ethyl 2-oxo-2-(1H-pyrrol-3-yl)acetate 
• 71616-57-4 ethyl 2-(3-pyrrolyl)acetate 
• 138779-98-3 N-tosyl-(1H-pyrrol-3-yl)acetic acid methyl ester 
• 81453-98-7 3-acetyl-1-(phenylsulfonyl)pyrrole 
• 106058-85-9 1-(1-tosyl-1H-pyrrol-3-yl)ethan-1-one 
• 86688-97-3 1-(Phenylsulfonyl)-3-(carbomethoxymethyl)pyrrole 

Downstream Products

• 1594128-72-9 C₂₈H₃₃N₃O₃ 
• 1253640-93-5 4-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylthio)carbonyl)-phenyl 2-(1H-pyrrol-3-yl)acetate 
• 1253640-92-4 4-((3,3,4,4,5,5,6,6,6-nonafluorohexylthio)carbonyl)phenyl 
• 1253640-94-6 4-((3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecylthio)carbonyl)-phenyl 2-(1H-pyrrol-3-yl)acetate 
• 132081-36-8 N-(pyrryl-3)acetyl-2-phenylglycine methyl ester 
• 50-00-0 formaldehyd 
• 1414702-04-7 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl 2-(1H-pyrrol-3-yl)acetate 
• 313663-81-9 4,6-dihydrocyclopenta[b]pyrrol-5(1H)-one 
• 134226-28-1 N-(p-vinylphenyl)-1-H-pyrrole-3-acetamide 
• 134226-30-5 N-(m-vinylphenyl)-1-H-pyrrole-3-acetamide 

Relevant articles and documents

Design, synthesis, and evaluation of 3-aryl-4-pyrrolyl-maleimides as glycogen synthase kinase-3β inhibitors

A series of 3-aryl-4-pyrrolyl-maleimides were designed, synthesized, and evaluated for their glycogen synthase kinase-3β (GSK-3β) inhibitory activity. Most compounds exhibited potent activity against GSK-3β. Among them, compounds 11a, 11c, 11h, 11i, and 11j significantly reduced Aβ-induced Tau hyperphosphorylation, showing the inhibition of GSK-3β at the cellular level. Structure-activity relationships were discussed based on the experimental data obtained. Most compounds in a new series of 3-aryl-4-pyrrolyl-maleimides exhibited potent glycogen synthase kinase-3β (GSK-3β) inhibitory activity. Compounds 11a, 11c, 11h, 11i, and 11j reduced Aβ-induced Tau hyperphosphorylation, showing inhibition of GSK-3β at the cellular level. Copyright

Superhydrophobic surfaces of electrodeposited polypyrroles bearing fluorinated liquid crystalline segments

Two intrinsic properties of fluorinated tails (F-butyl to F-octyl) were combined in the elaboration of superhydrophobic surfaces by electrochemical polymerization: their promesogenic characteristic and their ability to increase both hydrophobicity and oleophobicity. We report the synthesis and the characterization of pyrrole monomers bearing fluorinated liquid crystalline segments. The electrodeposited corresponding polymer films were characterized by cyclic voltammetry, static and dynamic contact angle measurements, and scanning electron microscopy. Sticky superhydrophobic surfaces were obtained with a F-hexyl or a F-octyl tail. The presence of mesogenic segments improves the surface hydrophobicity and increases the surface roughness, clearly observed with F-butyl and F-hexyl chains.

Poly[(3-pyrrolyl)acetic acid]

A poly[(3-pyrrolyl)acetic acid] is here disclosed which is represented by the formula (I) STR1 wherein n is an integer of 2 or more. This polymer can be prepared by subjecting (3-pyrrolyl)acetic acid to electrolytic oxidation polymerization in the presenc