138779-98-3

Upstream product

• 67-56-1 methanol 
• 106058-85-9 1-(1-tosyl-1H-pyrrol-3-yl)ethan-1-one 
• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 149-73-5 trimethyl orthoformate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 708259-63-6 3-(2-hydroxyethyl)-1-(p-toluenesulfonyl)pyrrole 
• 1253640-92-4 4-((3,3,4,4,5,5,6,6,6-nonafluorohexylthio)carbonyl)phenyl 
• 1253640-93-5 4-((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylthio)carbonyl)-phenyl 2-(1H-pyrrol-3-yl)acetate 
• 1253640-94-6 4-((3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecylthio)carbonyl)-phenyl 2-(1H-pyrrol-3-yl)acetate 
• 1414702-04-7 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl 2-(1H-pyrrol-3-yl)acetate 
• 936252-98-1 2-(3-(1-(p-toluenesulfonyl)pyrrolyl)ethyloxy)adenosine 
• 936252-89-0 6-chloro-2-(3''-(1''-(p-toluenesulfonyl)pyrrolyl)ethyloxy)-3',4',5'-triacetyladenosine 
• 936252-72-1 3-(2-iodoethyl)-1-(p-toluenesulfonyl)pyrrole 
• 86688-96-2 methyl 2-(1-tosyl-3-pyrrolyl)acetate 

Relevant academic research and scientific papers

Synthesis of novel pyrrolyl-indomethacin derivatives

In the present work, we report the synthesis of the novel esters of indomethacin (IDMC) and an ester of reduced IDMC. For this purpose, IDMC is covalently bound by using a spacer chain to the pyrrole (Py) in the 3-position. The innovative pyrrole-indomethacin (3-Py-IDMC) derivates show no cytotoxic effects in primary calvarial osteoblasts. The designed IDMC derivates have been studied because they could be injected locally as a component of polymeric micro-particles. In fact, the new 3-Py-IDMC derivatives will assure their further polymerization since the 2- and 5-monomer positions are free.

Superhydrophobic surfaces of electrodeposited polypyrroles bearing fluorinated liquid crystalline segments

Two intrinsic properties of fluorinated tails (F-butyl to F-octyl) were combined in the elaboration of superhydrophobic surfaces by electrochemical polymerization: their promesogenic characteristic and their ability to increase both hydrophobicity and oleophobicity. We report the synthesis and the characterization of pyrrole monomers bearing fluorinated liquid crystalline segments. The electrodeposited corresponding polymer films were characterized by cyclic voltammetry, static and dynamic contact angle measurements, and scanning electron microscopy. Sticky superhydrophobic surfaces were obtained with a F-hexyl or a F-octyl tail. The presence of mesogenic segments improves the surface hydrophobicity and increases the surface roughness, clearly observed with F-butyl and F-hexyl chains.

Pyrroles substituted by oligonucleotides

The invention relates to novel pyrrole derivatives of the formula (I) which make it possible to immobilize and address oligonucleotides by electropolymerization. Said invention also relates to thus produced electroactive polymers and to methods for using

Synthesis and polymerization of 2-(3-pyrrolyl)acetic acid derivatives from pyrrole

The synthesis of the 3-pyrrylacetic acid as well as the study of its esterification conditions are described. The new materials thus obtained are electropolymerized.